ACQUIRED RESISTANCE TO TUBERCULOUS INFECTION IN EXPERIMENTAL MODEL
نویسندگان
چکیده
منابع مشابه
An experimental model of chemotherapy on dormant tuberculous infection, with particular reference to rifampicin.
Mice were infected intravenously with a streptomycin (SM)-dependent strain of tubercle bacilli which had been starved of the antibiotic. The inoculum persisted in the spleen for a fairly long period, especially keeping almost the initial level of viable counts in the first few weeks. Isoniazid (INH) administration exerted little effect on such fate of the infection at a bactericidal dose to the...
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1. Mice with relatively great inherent resistance to certain bacterial infections were heavier but not more fertile than mice with relatively little inherent resistance. Mice with relatively little inherent resistance were with one exception not abnormally low in weight. 2. B. enteritidis given intrastomachally to susceptibles appeared in the blood stream more promptly, in larger numbers, and i...
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Results The i.v. and i.n. challenged mice showed significant DTH response. The CFU enumeration in eye did not show any bacilli initially by 30th day however tubercle bacilli could be recovered from the eyes of i.v. infected mice by 45 day at the time of death. Histopathology of these eyes showed inflammation with cluster of lymphocytes. The RTPCR for IS6110 gene from the eyes of i.n. infected a...
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Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity. In some disease systems, the process of waning immunity can be non-linear, involving a complex relationship between the duration of immunity and subsequent boosting of immunity through asymptomatic re-exposure. We present and anal...
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Clinical and parasitological traits of Sarcocystis miescheriana differ in Pietrain and Meishan pigs. For further description and characterization of the genetic basis of this variation a F(2) family based on Pietrain boars and Meishan sows as founders was generated. One hundred and thirty-nine F(2) pigs were challenged orally at an age of 100 days with 50,000 sporozysts to produce the typical c...
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ژورنال
عنوان ژورنال: Japanese Journal of Medical Science and Biology
سال: 1967
ISSN: 0021-5112,1884-2828
DOI: 10.7883/yoken1952.20.21